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HAIR LOSS
Compare options that help stimulate growth, lower DHT, block androgen effects or combine several approaches in one formula. We explain every ingredient, who each treatment is for, what the evidence shows and the side effects worth knowing.
Some treatments focus on growth. Others target hormones involved in pattern hair loss. Combination formulas do both. Compare the ingredients, format and price before you open a treatment page.
Active ingredients: Vitamin C + Zinc + Biotin + Iron + Niacinamide + Methylcobalamin
A topical vitamin-and-mineral formula that does not contain minoxidil, finasteride, dutasteride or spironolactone.
Why choose it
For someone who specifically wants a topical, nutrient-focused formula and wants to avoid the main prescription hair-loss drug mechanisms.
$75 per month
No membership fee · No clinician fee · Free shipping
Active ingredients: Minoxidil + Finasteride + Progesterone
A three-ingredient topical combining minoxidil for growth, finasteride to lower DHT, and progesterone, a steroid hormone.
Why choose it
For men who want minoxidil and a DHT blocker in one topical formula and prefer to avoid taking finasteride as a pill.
$75 per month
No membership fee · No clinician fee · Free shipping
Active ingredients: Minoxidil + Finasteride + Progesterone + Tretinoin
Power Hair Solution plus tretinoin: minoxidil + finasteride + progesterone + a prescription retinoid.
Why choose it
For men who want the same multi-mechanism topical as Power Hair Solution and are comfortable adding tretinoin to the formula.
$79 per month
No membership fee · No clinician fee · Free shipping
Active ingredients: Azelaic acid + Estradiol + Progesterone + Liothyronine
A highly customized topical containing azelaic acid plus three hormones: estradiol, progesterone and liothyronine (T3).
Why choose it
This is a clinician-guided hormone-containing topical for women. It is meaningfully different from standard minoxidil or spironolactone treatment.
$75 per month
No membership fee · No clinician fee · Free shipping
Active ingredients: Minoxidil + Finasteride + Tretinoin
A topical combination of minoxidil for growth, finasteride for DHT reduction and tretinoin, a prescription retinoid.
Why choose it
For men who want minoxidil + finasteride in one topical and are comfortable with tretinoin as part of the formula.
$79 per month
No membership fee · No clinician fee · Free shipping
Active ingredients: Minoxidil + Tretinoin + Fluocinolone + Biotin + Vitamin E
A minoxidil-based topical with tretinoin, fluocinolone, biotin and vitamin E, but no finasteride or dutasteride.
Why choose it
For someone who wants a multi-ingredient topical built around minoxidil while avoiding DHT-blocking medications.
$85 per month
No membership fee · No clinician fee · Free shipping
Active ingredients: Minoxidil + Finasteride + Tretinoin + Vitamin E + Fluocinolone
A five-ingredient topical combining minoxidil, finasteride, tretinoin, vitamin E and fluocinolone.
Why choose it
For men who want an all-in-one topical that addresses growth, DHT and scalp inflammation and are comfortable with a more complex formula.
$85 per month
No membership fee · No clinician fee · Free shipping
Active ingredients: Minoxidil + Finasteride
A straightforward two-ingredient topical: minoxidil for growth + finasteride to lower DHT.
Why choose it
For men who want both of the best-known medication approaches to male-pattern hair loss in one topical formula without added hormones, tretinoin or corticosteroids.
$79 per month
No membership fee · No clinician fee · Free shipping
Active ingredients: Finasteride + Minoxidil + Biotin
One oral capsule combining finasteride, low-dose oral minoxidil and biotin.
Why choose it
For men who want both DHT reduction and minoxidil without applying medication to the scalp.
$79 per month
No membership fee · No clinician fee · Free shipping
Active ingredients: Minoxidil + Spironolactone + Biotin
A women's oral combination of minoxidil + spironolactone + biotin.
Why choose it
For women who prefer an oral treatment and want both a hair-growth medication and an anti-androgen in one formula.
$79 per month
No membership fee · No clinician fee · Free shipping
Active ingredients: Minoxidil
A single-ingredient oral hair-loss option that avoids scalp application.
Why choose it
For people who want minoxidil but prefer a pill over a topical product.
$59 per month
No membership fee · No clinician fee · Free shipping
Active ingredients: Dutasteride
An oral DHT blocker that suppresses DHT more broadly than finasteride and is used off-label for hair loss in the U.S.
Why choose it
For men comparing a stronger DHT-lowering option, including some who have had an incomplete response to finasteride.
$59 per month
No membership fee · No clinician fee · Free shipping
Active ingredients: Spironolactone
An oral prescription medication with anti-androgen effects that is commonly used off-label for female-pattern hair loss.
Why choose it
Most relevant when androgen activity is believed to contribute to hair thinning.
$59 per month
No membership fee · No clinician fee · Free shipping
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Minoxidil does not block hormones. It helps keep hair follicles in the growth phase. Topical minoxidil is an established hair-loss treatment; low-dose oral minoxidil is also used off-label by clinicians.
DHT is a hormone made from testosterone and is a major driver of male-pattern hair loss. Finasteride and dutasteride are not hormones themselves. They block the enzyme that produces DHT.
Spironolactone is not a hormone. It is a prescription medication with anti-androgen effects and is commonly used off-label for female-pattern hair loss.
A combination can target more than one mechanism in one product, but every added ingredient also brings its own reason for being there, side effects and precautions. Avono explains each one by name.
HOW TO CHOOSE
Supports the growth phase of the hair cycle. Used by men and women, as a topical or a low-dose pill. It does not block DHT.
Lower DHT, the hormone behind male-pattern hair loss. Mainly used by men, and not for anyone who is or may become pregnant.
An anti-androgen commonly used off-label for female-pattern thinning. Often paired with minoxidil.
Oral or topical? Topicals keep treatment mostly on the scalp but need daily application. Pills are simpler but act on the whole body. In a 2024 randomized trial in men, oral minoxidil 5 mg was not superior to 5% topical minoxidil after 24 weeks; both improved hair density.
Minoxidil, finasteride or dutasteride? They work differently, which is why they are often combined. Oral finasteride 1 mg improved hair counts versus placebo over two years in trials of 1,553 men. Dutasteride lowers DHT more than finasteride and increased hair count more in a 24-week trial, but its hair-loss use in the U.S. is off-label.
One ingredient or a combination? Single ingredients make it easier to tell what is working and what is causing a side effect. Combination formulas cover more than one pathway in one product, with more ingredients that can irritate.
Men and women. Minoxidil is used by both. Finasteride and dutasteride are mainly for men. Spironolactone and the women’s formulas are designed for female-pattern thinning.
Tradeoffs and safety. Topicals can cause scalp irritation and early shedding. Oral minoxidil most often causes unwanted body or facial hair (about 15% in a study of 1,404 people). Finasteride can cause sexual side effects in a small minority. Spironolactone needs attention to potassium, kidney function and pregnancy.
Formulation context. These studies tested individual medicines. Avono’s compounded combinations were not themselves studied in these trials.
Sources: Penha 2024 (JAMA Dermatol); Kaufman 1998 (JAAD); Gubelin Harcha 2014 (JAAD); Vano-Galvan 2021 (JAAD); Spironolactone review (Cureus 2023).
Minoxidil is the most familiar growth-stimulating ingredient in the Avono catalog. It does not block DHT.
Finasteride and dutasteride reduce conversion of testosterone to DHT, a hormone strongly involved in male-pattern hair loss.
Spironolactone is commonly used off-label in women with androgen-related hair loss because of its anti-androgen effects.
Some compounded formulas combine minoxidil, a DHT blocker, tretinoin, anti-inflammatory ingredients or other components to address more than one pathway in a single treatment.
HOW IT WORKS
THE RESEARCH
Research on the medicines behind these treatments, including exactly what was studied. Study results describe the products and doses tested. They are not a prediction for any one person or for a compounded formulation.
FIND YOUR OPTIONS
Answer four quick questions and we'll narrow the treatments by audience, goal and format. A clinician decides what is medically appropriate.
These results are based on the preferences you selected, not a diagnosis or prescription.
Your secure clinical intake will open in a new tab.
Active ingredients: Vitamin C + Zinc + Biotin + Iron + Niacinamide + Methylcobalamin
A topical vitamin-and-mineral formula that does not contain minoxidil, finasteride, dutasteride or spironolactone.
Why choose it
For someone who specifically wants a topical, nutrient-focused formula and wants to avoid the main prescription hair-loss drug mechanisms.
$75 per month
No membership fee · No clinician fee · Free shipping
Active ingredients: Minoxidil + Finasteride + Progesterone
A three-ingredient topical combining minoxidil for growth, finasteride to lower DHT, and progesterone, a steroid hormone.
Why choose it
For men who want minoxidil and a DHT blocker in one topical formula and prefer to avoid taking finasteride as a pill.
$75 per month
No membership fee · No clinician fee · Free shipping
Active ingredients: Minoxidil + Finasteride + Progesterone + Tretinoin
Power Hair Solution plus tretinoin: minoxidil + finasteride + progesterone + a prescription retinoid.
Why choose it
For men who want the same multi-mechanism topical as Power Hair Solution and are comfortable adding tretinoin to the formula.
$79 per month
No membership fee · No clinician fee · Free shipping
Active ingredients: Azelaic acid + Estradiol + Progesterone + Liothyronine
A highly customized topical containing azelaic acid plus three hormones: estradiol, progesterone and liothyronine (T3).
Why choose it
This is a clinician-guided hormone-containing topical for women. It is meaningfully different from standard minoxidil or spironolactone treatment.
$75 per month
No membership fee · No clinician fee · Free shipping
Active ingredients: Minoxidil + Finasteride + Tretinoin
A topical combination of minoxidil for growth, finasteride for DHT reduction and tretinoin, a prescription retinoid.
Why choose it
For men who want minoxidil + finasteride in one topical and are comfortable with tretinoin as part of the formula.
$79 per month
No membership fee · No clinician fee · Free shipping
Active ingredients: Minoxidil + Tretinoin + Fluocinolone + Biotin + Vitamin E
A minoxidil-based topical with tretinoin, fluocinolone, biotin and vitamin E, but no finasteride or dutasteride.
Why choose it
For someone who wants a multi-ingredient topical built around minoxidil while avoiding DHT-blocking medications.
$85 per month
No membership fee · No clinician fee · Free shipping
Active ingredients: Minoxidil + Finasteride + Tretinoin + Vitamin E + Fluocinolone
A five-ingredient topical combining minoxidil, finasteride, tretinoin, vitamin E and fluocinolone.
Why choose it
For men who want an all-in-one topical that addresses growth, DHT and scalp inflammation and are comfortable with a more complex formula.
$85 per month
No membership fee · No clinician fee · Free shipping
Active ingredients: Minoxidil + Finasteride
A straightforward two-ingredient topical: minoxidil for growth + finasteride to lower DHT.
Why choose it
For men who want both of the best-known medication approaches to male-pattern hair loss in one topical formula without added hormones, tretinoin or corticosteroids.
$79 per month
No membership fee · No clinician fee · Free shipping
Active ingredients: Finasteride + Minoxidil + Biotin
One oral capsule combining finasteride, low-dose oral minoxidil and biotin.
Why choose it
For men who want both DHT reduction and minoxidil without applying medication to the scalp.
$79 per month
No membership fee · No clinician fee · Free shipping
Active ingredients: Minoxidil + Spironolactone + Biotin
A women's oral combination of minoxidil + spironolactone + biotin.
Why choose it
For women who prefer an oral treatment and want both a hair-growth medication and an anti-androgen in one formula.
$79 per month
No membership fee · No clinician fee · Free shipping
Active ingredients: Minoxidil
A single-ingredient oral hair-loss option that avoids scalp application.
Why choose it
For people who want minoxidil but prefer a pill over a topical product.
$59 per month
No membership fee · No clinician fee · Free shipping
Active ingredients: Dutasteride
An oral DHT blocker that suppresses DHT more broadly than finasteride and is used off-label for hair loss in the U.S.
Why choose it
For men comparing a stronger DHT-lowering option, including some who have had an incomplete response to finasteride.
$59 per month
No membership fee · No clinician fee · Free shipping
Active ingredients: Spironolactone
An oral prescription medication with anti-androgen effects that is commonly used off-label for female-pattern hair loss.
Why choose it
Most relevant when androgen activity is believed to contribute to hair thinning.
$59 per month
No membership fee · No clinician fee · Free shipping
Care & Safety
Some peptides and weight loss compounds are sold online with a “research use only” label. Here is what that label means, and how prescription care is different.
Care & Safety
Compounded medications are prepared by licensed pharmacies for individual prescriptions. They are not FDA-approved. Here is what that means in practice.
Weight Management
Both are used in clinician-guided weight management. One acts on one receptor, the other on two. A plain-language overview.
Explore the details or start your secure intake today. Clear treatment pricing, with no membership fee.