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For menTroche

Vardenafil Troche

A compounded dissolving form of vardenafil, another shorter-window PDE5 inhibitor.

Active ingredients: Vardenafil

$149

No membership fee · No clinician fee · Free shipping

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Vardenafil is an established PDE5 inhibitor. This compounded troche is not FDA-approved.

What it does

Vardenafil works through the same PDE5 mechanism as sildenafil and tadalafil. It is generally used as a planned, shorter-window ED medication rather than the longer-window option tadalafil provides.

What's in it

Vardenafil

What it is
PDE5 inhibitor.
Hormone?
Not a hormone.
Why it's here
Supports erectile response through increased blood-flow signaling during sexual stimulation.

Why choose this one?

Why choose this one

For men who want an alternative to sildenafil or tadalafil or prefer a dissolving troche.

Why choose Tadalafil Tablet or Sildenafil + Pycnogenol ODT instead?

Tadalafil offers more timing flexibility. Sildenafil has a larger body of familiar consumer use and may be the simpler shorter-window comparison.

Compare your options

Sildenafil vs tadalafil

Sildenafil (and vardenafil)Tadalafil
Treatment typePDE5 inhibitor, shorter-actingPDE5 inhibitor, longer-acting
Who it's forMenMen
Typical useTaken about an hour before sexTaken before sex, with a much longer window
How long it can workSeveral hoursStill effective at 36 hours in a clinical study
FoodA large, high-fat meal can delay standard tabletsAbsorption not meaningfully affected by food
Common side effectsHeadache, flushing, indigestion, stuffy nose, vision tintHeadache, indigestion, back pain, muscle aches, flushing
Never combine withNitrate medicinesNitrate medicines
Price at AvonoFrom $60 for 6 dosesFrom $60 for 6 doses

Duration and food findings come from standard FDA-approved tablets. Compounded dissolving formats were not studied in those trials.

Tablet vs dissolving formats

Standard tabletODT or troche
How it's takenSwallowed with waterDissolves in the mouth
EvidenceThe format used in the main clinical trialsCompounded formats were not themselves studied in those trials
IngredientsA single medicineSome combine a second ingredient
Who may prefer itPeople who want the most-studied formatPeople who prefer not to swallow pills
Price at AvonoFrom $99From $60 for 6 doses

Benefits and evidence

Vardenafil at-home randomized trial

What the study found
580 men
Who was studied
580 men with erectile dysfunction
What it means
In a randomized clinical trial, vardenafil significantly improved erectile-function measures versus placebo.
Important context
Studied vardenafil in a standard oral form. The compounded troche was not itself studied. Oral vardenafil · Several doses, including 20 mg
Sources
  1. Vardenafil prescribing information, DailyMed
  2. The efficacy and tolerability of vardenafil: the first at-home clinical trial. Int J Impot Res. 2001

Common side effects

Headache, flushing, nasal congestion, indigestion and dizziness.

What may help

Headache, flushing and a stuffy nose are the most common side effects and are usually mild and short-lived. General measures that may help:

  • Stay hydrated, and keep alcohol moderate; heavy drinking makes dizziness and low blood pressure more likely and can itself worsen erections.
  • With standard sildenafil tablets, a large or high-fat meal can delay the effect.
  • Do not take more than prescribed, and do not combine with other erection medicines.

If side effects bother you, your clinician can review the plan.

Important safety information

Vardenafil has a specific QT-prolongation warning and may not be appropriate with certain heart-rhythm conditions or antiarrhythmic drugs. Never use it with nitrates.

Do not use a PDE5 inhibitor with nitrate medications. The combination can cause a dangerous drop in blood pressure.

PDE5 inhibitors must not be used with nitrate medications because the combination can cause dangerous blood-pressure lowering. Other cardiovascular history, alpha blockers and interacting drugs matter.

Nitrates are contraindicated. Vardenafil has a specific QT-prolongation concern and should be avoided in patients with congenital QT prolongation or certain Class IA/Class III antiarrhythmics. Compounded troche, not FDA-approved.

This is a compounded medication. Compounded medications are prepared by licensed pharmacies and are not FDA-approved.

Prescription treatments require evaluation by a licensed clinician and are not appropriate for everyone. Some of these medications can interact with other medications, including nitrates. Compounded formulas are not FDA-approved. Not available in all states.

When to contact your clinician

Contact your clinician about fainting or significant dizziness, especially if you take blood-pressure medicines or alpha-blockers.

When to seek urgent care

Seek emergency care for an erection lasting more than 4 hours, sudden loss of vision in one or both eyes, sudden hearing loss (sometimes with ringing or dizziness), or chest pain during or after sex. Tell responders you took an erection medicine, because nitrates must not be given soon afterwards.

Questions people ask

Is this a hormone?

No. Vardenafil is a PDE5 inhibitor, not a hormone.

Does it increase libido?

No. PDE5 inhibitors are not aphrodisiacs. They do not create sexual desire on their own; they support erectile response during sexual stimulation.

What happens if I use nitrates?

PDE5 inhibitors must not be used with nitrate medications because the combination can cause dangerous blood-pressure lowering. Other cardiovascular history, alpha blockers and interacting drugs matter.

Can I drink alcohol with it?

Moderate drinking is usually acceptable, but heavy drinking with a PDE5 inhibitor makes dizziness, a fast heartbeat and low blood pressure more likely, and alcohol itself can make erections harder to get. Ask your clinician what is sensible for you.

Will it increase my sex drive?

No. PDE5 inhibitors support blood flow in response to sexual stimulation. They do not create desire. If low desire is the main concern, mention it to your clinician because it can have other causes.

How is vardenafil different from sildenafil?

Both are shorter-acting PDE5 inhibitors that work through the same pathway. People sometimes try one after the other did not suit them. Your clinician can explain which fits your health and medicines.

Discuss Vardenafil Troche with a licensed clinician

Your clinician reviews your health history and decides whether this option, or another, is appropriate.

$149

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